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  1. Glossary
  2. Crossover Design
Crossover Design - Glossary Term Illustration

Crossover Design

Crossover design is a quasi-experimental design used in longitudinal, repeated measures studies. In this design, each group receives both treatments at different times. This study design has the advantage of every individual serving as their own control, which may reduce the influence of confounding variables. However, the design itself introduces the chances that anyone receiving the experimental variable in the first period will continue to be affected in the second period.

Crossover Design

Crossover (Study) Design: A type of longitudinal, repeated measures quasi-experimental design in which each group receives both treatments, but at different times. It is named "crossover" due to the patients' "crossing-over" to the other treatment or sham group after a specified period of time.

  • This type of study has the advantage of every individual serving as their own control, which may reduce the influence of confounding variables.
  • Unfortunately, the design itself introduces the chances that anyone receiving the experimental variable in the first period will continue to be effected in the second period.

In a study by Senna et al., a cross-over design was used to investigate the difference load made on inter-set rest intervals (1).

  1. Senna, G.W., Rodrigues, B.M., Sandy, Scudese, Bianco, A, & Dantas, E.H.M. (2017). Heavy vs light load single-joint exercise performance with different intervals. Journal of Human Kinetics, 58, 197-206.

Image Reference: Design, Analysis, and Reporting of Crossover Trials for Inclusion in a Meta-Analysis - Scientific Figure on ResearchGate. Available from: https://www.researchgate.net/figure/Illustration-of-the-design-and-analysis-of-a-crossover-trial-Carryover-effect-If-A-is_fig7_281173748 [accessed 31 May, 2023]

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